Endocrine Abstracts

Introduction: Thyroid hormones have major effects on regulation of metabolism and function of most cells. A number of prevalent diseases during adulthood have been attributed to the intrauterine status during fetal life. In this study, the effect of fetal hypothyroidism on the carbohydrate metabolism during adulthood investigated.Subject and methods: After mating, the pregnant rats were divided in two, the fetal hypothyroidism (FH) and the control (C) gr...

Introduction: Any abnormalities during pregnancy can affect the growth and development of the fetus and may have a long lasting effect presented during adulthood (intrauterine programming). In this study, the effect of maternal hypothyroidism on insulin secretion from the isolated islets of offspring has been investigated in male rats.Materials and methods: In Test group maternal hypothyroidism was induced using 0.02% propylthiouracyl in drinking water t...